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GLP-1 and Prescription Weight Loss Medications Prescription medication may be one part of a physician-led medical weight loss plan

Drugs metabolized by CYP3A (certain statins, blood thinners, antiarrhythmics, immunosuppressants, migraine medications, antidepressants) may interact

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However Lillys demonstration that a GIP/GLP-1 receptor co-agonist (tirzepatide) has superior efficacy compared to selective GLP-1 receptor agonists, has renewed interest in the first incretin. Lilly rolled out their SURPASS trials to position their agent amongst existing diabetes medications and GLP-1 agonists